The Audi S5 Cabriolet (2018-2024) is the drop-top version of the redesigned second-generation A5's performance model, sharing the Coupe's new turbocharged 3.0-liter TFSI V6, 8-speed Tiptronic automatic, and quattro all-wheel drive. Like the Coupe, no manual transmission was ever offered.

As with any convertible, the folding top and added structure carry a weight penalty versus the closed-roof body styles (see the 'Weight vs. S5 Coupe' fact for the figure).